Association of “hypertriglyceridemic waist” with increased 5-year risk of subclinical atherosclerosis in a multi-ethnic population: a prospective cohort study

Abstract Background Hypertriglyceridemic waist (HTGW), which incorporates measures of circumference and levels triglyceride in blood, could act as an early-stage predictor to identify the individuals at high-risk for subclinical atherosclerosis. Previous studies have explored cross-sectional association between HTGW atherosclerosis; however, understanding how this might change over time is necessary. This study will assess with 5-year carotid Methods 517 participants Aboriginal, Chinese, European, South Asian ethnicities were examined baseline indices atherosclerosis (intima media thickness (mm), total area (mm 2 ), plaque presence). Family history cardiovascular disease, sociodemographic (age, sex, ethnicity, income level, maximum education), traditional risk factors (systolic blood pressure, smoking status, cholesterol, high-density lipoprotein body mass index) incorporated into models association. These used multiple linear regression logistic regression. Results Baseline phenotype a statistically significant clinically meaningful intima (? = 0.08 [0.04, 0.11], p < 0.001), 0.20 [0.07, 0.33], 0.002), presence (OR 2.17 [1.13, 4.19], 0.02) compared non-HTGW group independent family history. However, no longer after adjusting ( 0.27, 0.45, 0.66, respectively). Moreover, status does not correlate 5 years. Conclusions Our results suggest that when are known, may offer additional value progression